BDBM50186678 (+/-)-3-difluoromethyl-7-trifluoromethyl-1,2,3,4-tetrahydroisoquinoline::CHEMBL206892
SMILES: FC(F)C1Cc2ccc(cc2CN1)C(F)(F)F
InChI Key: InChIKey=YJPNCPSOYFPBLF-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Phenylethanolamine N-methyltransferase (Homo sapiens (Human)) | BDBM50186678 ((+/-)-3-difluoromethyl-7-trifluoromethyl-1,2,3,4-t...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 67 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas Curated by ChEMBL | Assay Description Binding affinity to human PNMT | J Med Chem 49: 2939-52 (2006) Article DOI: 10.1021/jm051262k BindingDB Entry DOI: 10.7270/Q2K64HQ3 | |||||||||||
More data for this Ligand-Target Pair |