BindingDB PrimarySearch

BDBM50186733 CHEMBL208152::L-1,4,6-trideoxy-4,4-difluoronojirimycin

SMILES: C[C@@H]1NC[C@@H](O)[C@H](O)C1(F)F

InChI Key: InChIKey=PPFKZUHHAXUCRZ-LMVFSUKVSA-N

Data: 9 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50186733
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Alpha-L-fucosidase I (Homo sapiens (Human))	BDBM50186733 (CHEMBL208152 \| L-1,4,6-trideoxy-4,4-difluoronojiri...) Show SMILES C[C@@H]1NC[C@@H](O)[C@H](O)C1(F)F Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a	6.8	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human placenta alpha fucosidase at pH 6.8				J Med Chem 49: 2989-97 (2006) Article DOI: 10.1021/jm060066q BindingDB Entry DOI: 10.7270/Q29P318F
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-L-fucosidase 1 (Bos taurus)	BDBM50186733 (CHEMBL208152 \| L-1,4,6-trideoxy-4,4-difluoronojiri...) Show SMILES C[C@@H]1NC[C@@H](O)[C@H](O)C1(F)F Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.70E+5	n/a	n/a	n/a	n/a	n/a	n/a	6.8	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of bovine kidney alpha fucosidase at pH 6.8				J Med Chem 49: 2989-97 (2006) Article DOI: 10.1021/jm060066q BindingDB Entry DOI: 10.7270/Q29P318F
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-glucosidase (Hansenula anomala)	BDBM50186733 (CHEMBL208152 \| L-1,4,6-trideoxy-4,4-difluoronojiri...) Show SMILES C[C@@H]1NC[C@@H](O)[C@H](O)C1(F)F Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	6.8	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of Saccharomyces fragilis beta glucosidase at pH 6.8				J Med Chem 49: 2989-97 (2006) Article DOI: 10.1021/jm060066q BindingDB Entry DOI: 10.7270/Q29P318F
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-mannosidase (Homo sapiens (Human))	BDBM50186733 (CHEMBL208152 \| L-1,4,6-trideoxy-4,4-difluoronojiri...) Show SMILES C[C@@H]1NC[C@@H](O)[C@H](O)C1(F)F Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	4.0	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of snail beta mannosidase at pH 4				J Med Chem 49: 2989-97 (2006) Article DOI: 10.1021/jm060066q BindingDB Entry DOI: 10.7270/Q29P318F
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-mannosidase (Glycine max)	BDBM50186733 (CHEMBL208152 \| L-1,4,6-trideoxy-4,4-difluoronojiri...) Show SMILES C[C@@H]1NC[C@@H](O)[C@H](O)C1(F)F Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	6.8	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of jack bean alpha mannosidase at pH 6.8				J Med Chem 49: 2989-97 (2006) Article DOI: 10.1021/jm060066q BindingDB Entry DOI: 10.7270/Q29P318F
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-galactosidase (Coffea arabica)	BDBM50186733 (CHEMBL208152 \| L-1,4,6-trideoxy-4,4-difluoronojiri...) Show SMILES C[C@@H]1NC[C@@H](O)[C@H](O)C1(F)F Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	6.8	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of green coffee beans alpha galactosidase at pH 6.8				J Med Chem 49: 2989-97 (2006) Article DOI: 10.1021/jm060066q BindingDB Entry DOI: 10.7270/Q29P318F
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-glucosidase (Aspergillus aculeatus)	BDBM50186733 (CHEMBL208152 \| L-1,4,6-trideoxy-4,4-difluoronojiri...) Show SMILES C[C@@H]1NC[C@@H](O)[C@H](O)C1(F)F Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	6.8	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of Aspergillus oryzae beta glucosidase at pH 6.8				J Med Chem 49: 2989-97 (2006) Article DOI: 10.1021/jm060066q BindingDB Entry DOI: 10.7270/Q29P318F
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-mannosidase (Glycine max)	BDBM50186733 (CHEMBL208152 \| L-1,4,6-trideoxy-4,4-difluoronojiri...) Show SMILES C[C@@H]1NC[C@@H](O)[C@H](O)C1(F)F Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	6.8	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of jack bean alpha mannosidase at pH 6.8				J Med Chem 49: 2989-97 (2006) Article DOI: 10.1021/jm060066q BindingDB Entry DOI: 10.7270/Q29P318F
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-glucosidase (Prunus avium)	BDBM50186733 (CHEMBL208152 \| L-1,4,6-trideoxy-4,4-difluoronojiri...) Show SMILES C[C@@H]1NC[C@@H](O)[C@H](O)C1(F)F Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	6.8	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of almond beta glucosidase at pH 6.8				J Med Chem 49: 2989-97 (2006) Article DOI: 10.1021/jm060066q BindingDB Entry DOI: 10.7270/Q29P318F
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair