BDBM50186768 CHEMBL212750::N-(3-chloro-4-fluoro-phenyl)-2-[1-cyclopentyl-4-(3',5'-difluoro-biphenyl-4-yl)-piperidin-4-ylamino]-acetamide

SMILES: Fc1cc(F)cc(c1)-c1ccc(cc1)C1(CCN(CC1)C1CCCC1)NCC(=O)Nc1ccc(F)c(Cl)c1

InChI Key: InChIKey=NUSNPTQIBDKHCJ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50186768   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50186768 (CHEMBL212750 | N-(3-chloro-4-fluoro-phenyl)-2-[1-c...) Show SMILES Fc1cc(F)cc(c1)-c1ccc(cc1)C1(CCN(CC1)C1CCCC1)NCC(=O)Nc1ccc(F)c(Cl)c1 Show InChI InChI=1S/C30H31ClF3N3O/c31-27-18-25(9-10-28(27)34)36-29(38)19-35-30(11-13-37(14-12-30)26-3-1-2-4-26)22-7-5-20(6-8-22)21-15-23(32)17-24(33)16-21/h5-10,15-18,26,35H,1-4,11-14,19H2,(H,36,38)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	141	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human MCHR1 assessed as inhibition of MCH-mediated calcium ion influx by FLIPR assay				Bioorg Med Chem Lett 16: 3668-73 (2006) Article DOI: 10.1016/j.bmcl.2006.04.061 BindingDB Entry DOI: 10.7270/Q2251HT9
					More data for this Ligand-Target Pair
GPR145 (Homo sapiens (Human))	BDBM50186768 (CHEMBL212750 | N-(3-chloro-4-fluoro-phenyl)-2-[1-c...) Show SMILES Fc1cc(F)cc(c1)-c1ccc(cc1)C1(CCN(CC1)C1CCCC1)NCC(=O)Nc1ccc(F)c(Cl)c1 Show InChI InChI=1S/C30H31ClF3N3O/c31-27-18-25(9-10-28(27)34)36-29(38)19-35-30(11-13-37(14-12-30)26-3-1-2-4-26)22-7-5-20(6-8-22)21-15-23(32)17-24(33)16-21/h5-10,15-18,26,35H,1-4,11-14,19H2,(H,36,38)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human MCHR2 assessed as inhibition of MCH-mediated calcium ion influx by FLIPR assay				Bioorg Med Chem Lett 16: 3668-73 (2006) Article DOI: 10.1016/j.bmcl.2006.04.061 BindingDB Entry DOI: 10.7270/Q2251HT9
					More data for this Ligand-Target Pair