null

SMILES: CN(CC(=O)Nc1cc(F)cc(F)c1)C1(CCN(CC1)C1CCCC1)c1ccc(cc1)-c1cccc(c1)C#N

InChI Key: InChIKey=KULCUMUGLWUBMF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50186777   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50186777 (2-{[4-(3'-cyano-biphenyl-4-yl)-1-cyclopentyl-piper...) Show SMILES CN(CC(=O)Nc1cc(F)cc(F)c1)C1(CCN(CC1)C1CCCC1)c1ccc(cc1)-c1cccc(c1)C#N Show InChI InChI=1S/C32H34F2N4O/c1-37(22-31(39)36-29-19-27(33)18-28(34)20-29)32(13-15-38(16-14-32)30-7-2-3-8-30)26-11-9-24(10-12-26)25-6-4-5-23(17-25)21-35/h4-6,9-12,17-20,30H,2-3,7-8,13-16,22H2,1H3,(H,36,39)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human MCHR1 assessed as inhibition of MCH-mediated calcium ion influx by FLIPR assay				Bioorg Med Chem Lett 16: 3668-73 (2006) Article DOI: 10.1016/j.bmcl.2006.04.061 BindingDB Entry DOI: 10.7270/Q2251HT9
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 2 (Homo sapiens (Human))	BDBM50186777 (2-{[4-(3'-cyano-biphenyl-4-yl)-1-cyclopentyl-piper...) Show SMILES CN(CC(=O)Nc1cc(F)cc(F)c1)C1(CCN(CC1)C1CCCC1)c1ccc(cc1)-c1cccc(c1)C#N Show InChI InChI=1S/C32H34F2N4O/c1-37(22-31(39)36-29-19-27(33)18-28(34)20-29)32(13-15-38(16-14-32)30-7-2-3-8-30)26-11-9-24(10-12-26)25-6-4-5-23(17-25)21-35/h4-6,9-12,17-20,30H,2-3,7-8,13-16,22H2,1H3,(H,36,39)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human MCHR2 assessed as inhibition of MCH-mediated calcium ion influx by FLIPR assay				Bioorg Med Chem Lett 16: 3668-73 (2006) Article DOI: 10.1016/j.bmcl.2006.04.061 BindingDB Entry DOI: 10.7270/Q2251HT9
					More data for this Ligand-Target Pair