BDBM50186786 3-[4-(3'-cyano-biphenyl-4-yl)-1-cyclopentyl-piperidin-4-yl]-N-(3,4-difluoro-phenyl)-propionamide::CHEMBL209089

SMILES: Fc1ccc(NC(=O)CCC2(CCN(CC2)C2CCCC2)c2ccc(cc2)-c2cccc(c2)C#N)cc1F

InChI Key: InChIKey=DIRDEJWHHBAMET-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50186786   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50186786 (3-[4-(3'-cyano-biphenyl-4-yl)-1-cyclopentyl-piperi...) Show SMILES Fc1ccc(NC(=O)CCC2(CCN(CC2)C2CCCC2)c2ccc(cc2)-c2cccc(c2)C#N)cc1F Show InChI InChI=1S/C32H33F2N3O/c33-29-13-12-27(21-30(29)34)36-31(38)14-15-32(16-18-37(19-17-32)28-6-1-2-7-28)26-10-8-24(9-11-26)25-5-3-4-23(20-25)22-35/h3-5,8-13,20-21,28H,1-2,6-7,14-19H2,(H,36,38)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human MCHR1 assessed as inhibition of MCH-mediated calcium ion influx by FLIPR assay				Bioorg Med Chem Lett 16: 3668-73 (2006) Article DOI: 10.1016/j.bmcl.2006.04.061 BindingDB Entry DOI: 10.7270/Q2251HT9
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 2 (Homo sapiens (Human))	BDBM50186786 (3-[4-(3'-cyano-biphenyl-4-yl)-1-cyclopentyl-piperi...) Show SMILES Fc1ccc(NC(=O)CCC2(CCN(CC2)C2CCCC2)c2ccc(cc2)-c2cccc(c2)C#N)cc1F Show InChI InChI=1S/C32H33F2N3O/c33-29-13-12-27(21-30(29)34)36-31(38)14-15-32(16-18-37(19-17-32)28-6-1-2-7-28)26-10-8-24(9-11-26)25-5-3-4-23(20-25)22-35/h3-5,8-13,20-21,28H,1-2,6-7,14-19H2,(H,36,38)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human MCHR2 assessed as inhibition of MCH-mediated calcium ion influx by FLIPR assay				Bioorg Med Chem Lett 16: 3668-73 (2006) Article DOI: 10.1016/j.bmcl.2006.04.061 BindingDB Entry DOI: 10.7270/Q2251HT9
					More data for this Ligand-Target Pair