null
SMILES: Clc1cc(Cl)cc(NC(=O)COC2(CCN(CC2)C2CCCC2)c2ccc(cc2)-c2cccc(c2)C#N)c1
InChI Key: InChIKey=VVQXSDPLKCPWGQ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50186806 (2-[4-(3'-cyano-biphenyl-4-yl)-1-cyclopentyl-piperi...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering Plough Research Institute Curated by ChEMBL | Assay Description Binding affinity at human MCHR1 assessed as inhibition of MCH-mediated calcium ion influx by FLIPR assay | Bioorg Med Chem Lett 16: 3668-73 (2006) Article DOI: 10.1016/j.bmcl.2006.04.061 BindingDB Entry DOI: 10.7270/Q2251HT9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 2 (Homo sapiens (Human)) | BDBM50186806 (2-[4-(3'-cyano-biphenyl-4-yl)-1-cyclopentyl-piperi...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering Plough Research Institute Curated by ChEMBL | Assay Description Binding affinity at human MCHR2 assessed as inhibition of MCH-mediated calcium ion influx by FLIPR assay | Bioorg Med Chem Lett 16: 3668-73 (2006) Article DOI: 10.1016/j.bmcl.2006.04.061 BindingDB Entry DOI: 10.7270/Q2251HT9 | |||||||||||
More data for this Ligand-Target Pair |