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BDBM50186943 1-(4-bromophenyl)-3-(2,3-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-4-yl)urea::CHEMBL377969

SMILES: Cc1c(NC(=O)Nc2ccc(Br)cc2)c(=O)n(-c2ccccc2)n1C

InChI Key: InChIKey=AFNFUDZGKRZEER-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50186943   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
fMet-Leu-Phe receptor 1/2


(Homo sapiens (human))
BDBM50186943
PNG
(1-(4-bromophenyl)-3-(2,3-dimethyl-5-oxo-1-phenyl-2...)
Show SMILES Cc1c(NC(=O)Nc2ccc(Br)cc2)c(=O)n(-c2ccccc2)n1C
Show InChI InChI=1S/C18H17BrN4O2/c1-12-16(21-18(25)20-14-10-8-13(19)9-11-14)17(24)23(22(12)2)15-6-4-3-5-7-15/h3-11H,1-2H3,(H2,20,21,25)
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Similars

Article
PubMed
n/an/an/an/a 90n/an/an/an/a



Amgen, Inc.

Curated by ChEMBL


Assay Description
Activity at human FPRL1-mediated calcium mobilization in CHO cells


Bioorg Med Chem Lett 16: 3713-8 (2006)

More data for this
Ligand-Target Pair