BDBM50186953 1-(3-isopropyl-2-methyl-5-oxo-1-(quinolin-3-yl)-2,5-dihydro-1H-pyrazol-4-yl)-3-(4-(trifluoromethyl)phenyl)urea::CHEMBL380389

SMILES: CC(C)c1c(NC(=O)Nc2ccc(cc2)C(F)(F)F)c(=O)n(-c2cnc3ccccc3c2)n1C

InChI Key: InChIKey=GWBITAQAPMSVBY-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50186953   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM50186953 (1-(3-isopropyl-2-methyl-5-oxo-1-(quinolin-3-yl)-2,...) Show SMILES CC(C)c1c(NC(=O)Nc2ccc(cc2)C(F)(F)F)c(=O)n(-c2cnc3ccccc3c2)n1C Show InChI InChI=1S/C24H22F3N5O2/c1-14(2)21-20(30-23(34)29-17-10-8-16(9-11-17)24(25,26)27)22(33)32(31(21)3)18-12-15-6-4-5-7-19(15)28-13-18/h4-14H,1-3H3,(H2,29,30,34)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	44	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Activity at human FPRL1-mediated calcium mobilization in CHO cells				Bioorg Med Chem Lett 16: 3713-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.068 BindingDB Entry DOI: 10.7270/Q2DF6QTJ
					More data for this Ligand-Target Pair