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BDBM50186958 1-(2-ethyl-3-isopropyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-4-yl)-3-(3-fluoro-4-methylphenyl)urea::CHEMBL378064

SMILES: CCn1c(C(C)C)c(NC(=O)Nc2ccc(C)c(F)c2)c(=O)n1-c1ccccc1

InChI Key: InChIKey=NNZGZRJBRZYXCJ-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50186958   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
fMet-Leu-Phe receptor 1/2


(Homo sapiens (human))
BDBM50186958
PNG
(1-(2-ethyl-3-isopropyl-5-oxo-1-phenyl-2,5-dihydro-...)
Show SMILES CCn1c(C(C)C)c(NC(=O)Nc2ccc(C)c(F)c2)c(=O)n1-c1ccccc1
Show InChI InChI=1S/C22H25FN4O2/c1-5-26-20(14(2)3)19(21(28)27(26)17-9-7-6-8-10-17)25-22(29)24-16-12-11-15(4)18(23)13-16/h6-14H,5H2,1-4H3,(H2,24,25,29)
NCI pathway
Reactome pathway
KEGG

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Similars

Article
PubMed
n/an/an/an/a 100n/an/an/an/a



Amgen, Inc.

Curated by ChEMBL


Assay Description
Activity at human FPRL1-mediated calcium mobilization in CHO cells


Bioorg Med Chem Lett 16: 3713-8 (2006)

More data for this
Ligand-Target Pair