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BDBM50186963 1-(4-chlorophenyl)-3-(3-isopropyl-2-methyl-5-oxo-1-(quinolin-3-yl)-2,5-dihydro-1H-pyrazol-4-yl)urea::CHEMBL210303

SMILES: CC(C)c1c(NC(=O)Nc2ccc(Cl)cc2)c(=O)n(-c2cnc3ccccc3c2)n1C

InChI Key: InChIKey=DADHGAUCQHEAGZ-UHFFFAOYSA-N

Data: 1 EC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50186963   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM50186963
PNG
(1-(4-chlorophenyl)-3-(3-isopropyl-2-methyl-5-oxo-1...)
Show SMILES CC(C)c1c(NC(=O)Nc2ccc(Cl)cc2)c(=O)n(-c2cnc3ccccc3c2)n1C
Show InChI InChI=1S/C23H22ClN5O2/c1-14(2)21-20(27-23(31)26-17-10-8-16(24)9-11-17)22(30)29(28(21)3)18-12-15-6-4-5-7-19(15)25-13-18/h4-14H,1-3H3,(H2,26,27,31)
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 80n/an/an/an/a



Amgen, Inc.

Curated by ChEMBL


Assay Description
Activity at human FPRL1-mediated calcium mobilization in CHO cells


Bioorg Med Chem Lett 16: 3713-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.04.068
BindingDB Entry DOI: 10.7270/Q2DF6QTJ
More data for this
Ligand-Target Pair