BDBM50186963 1-(4-chlorophenyl)-3-(3-isopropyl-2-methyl-5-oxo-1-(quinolin-3-yl)-2,5-dihydro-1H-pyrazol-4-yl)urea::CHEMBL210303

SMILES: CC(C)c1c(NC(=O)Nc2ccc(Cl)cc2)c(=O)n(-c2cnc3ccccc3c2)n1C

InChI Key: InChIKey=DADHGAUCQHEAGZ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50186963   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM50186963 (1-(4-chlorophenyl)-3-(3-isopropyl-2-methyl-5-oxo-1...) Show SMILES CC(C)c1c(NC(=O)Nc2ccc(Cl)cc2)c(=O)n(-c2cnc3ccccc3c2)n1C Show InChI InChI=1S/C23H22ClN5O2/c1-14(2)21-20(27-23(31)26-17-10-8-16(24)9-11-17)22(30)29(28(21)3)18-12-15-6-4-5-7-19(15)25-13-18/h4-14H,1-3H3,(H2,26,27,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	80	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Activity at human FPRL1-mediated calcium mobilization in CHO cells				Bioorg Med Chem Lett 16: 3713-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.068 BindingDB Entry DOI: 10.7270/Q2DF6QTJ
					More data for this Ligand-Target Pair