BDBM50186967 1-(2,3-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-4-yl)-3-(4-fluoro-3-methylphenyl)urea::CHEMBL210526

SMILES: Cc1c(NC(=O)Nc2ccc(F)c(C)c2)c(=O)n(-c2ccccc2)n1C

InChI Key: InChIKey=XBLNZURYCFOENF-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50186967   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM50186967 (1-(2,3-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyra...) Show SMILES Cc1c(NC(=O)Nc2ccc(F)c(C)c2)c(=O)n(-c2ccccc2)n1C Show InChI InChI=1S/C19H19FN4O2/c1-12-11-14(9-10-16(12)20)21-19(26)22-17-13(2)23(3)24(18(17)25)15-7-5-4-6-8-15/h4-11H,1-3H3,(H2,21,22,26)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Activity at human FPRL1-mediated calcium mobilization in CHO cells				Bioorg Med Chem Lett 16: 3713-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.068 BindingDB Entry DOI: 10.7270/Q2DF6QTJ
					More data for this Ligand-Target Pair