BDBM50186968 1-(3-isopropyl-2-methyl-5-oxo-1-(pyrimidin-5-yl)-2,5-dihydro-1H-pyrazol-4-yl)-3-(4-(methylthio)phenyl)urea::CHEMBL211220

SMILES: CSc1ccc(NC(=O)Nc2c(C(C)C)n(C)n(-c3cncnc3)c2=O)cc1

InChI Key: InChIKey=MKWQMWMCGACQFF-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50186968   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM50186968 (1-(3-isopropyl-2-methyl-5-oxo-1-(pyrimidin-5-yl)-2...) Show SMILES CSc1ccc(NC(=O)Nc2c(C(C)C)n(C)n(-c3cncnc3)c2=O)cc1 Show InChI InChI=1S/C19H22N6O2S/c1-12(2)17-16(18(26)25(24(17)3)14-9-20-11-21-10-14)23-19(27)22-13-5-7-15(28-4)8-6-13/h5-12H,1-4H3,(H2,22,23,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	43	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Activity at human FPRL1-mediated calcium mobilization in CHO cells				Bioorg Med Chem Lett 16: 3713-8 (2006) Article DOI: 10.1016/j.bmcl.2006.04.068 BindingDB Entry DOI: 10.7270/Q2DF6QTJ
					More data for this Ligand-Target Pair