BDBM50187017 CHEMBL380052::methyl 3-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-2-hydroxybenzoate

SMILES: COC(=O)c1cccc(Nc2c(Nc3ccccc3)c(=O)c2=O)c1O

InChI Key: InChIKey=KRCLVQVTBIBHIQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50187017   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50187017 (CHEMBL380052 | methyl 3-(3,4-dioxo-2-(phenylamino)...) Show SMILES COC(=O)c1cccc(Nc2c(Nc3ccccc3)c(=O)c2=O)c1O Show InChI InChI=1S/C18H14N2O5/c1-25-18(24)11-8-5-9-12(15(11)21)20-14-13(16(22)17(14)23)19-10-6-3-2-4-7-10/h2-9,19-21H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacopeia Drug Discovery, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]IL8 from human CXCR2 expressed in CHO cells				Bioorg Med Chem Lett 16: 4107-10 (2006) Article DOI: 10.1016/j.bmcl.2006.04.082 BindingDB Entry DOI: 10.7270/Q24X57DB
					More data for this Ligand-Target Pair