BDBM50187083 6-(4-methoxyphenethylamino)-N-(2-aminophenyl)nicotinamide::CHEMBL379516
SMILES: COc1ccc(CCNc2ccc(cn2)C(=O)Nc2ccccc2N)cc1
InChI Key: InChIKey=YIEZALBXLNXYSW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50187083 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50187083
(6-(4-methoxyphenethylamino)-N-(2-aminophenyl)nicot...)Show InChI InChI=1S/C21H22N4O2/c1-27-17-9-6-15(7-10-17)12-13-23-20-11-8-16(14-24-20)21(26)25-19-5-3-2-4-18(19)22/h2-11,14H,12-13,22H2,1H3,(H,23,24)(H,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Menarini Ricerche
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
J Med Chem 51: 1505-29 (2008)
Article DOI: 10.1021/jm7011408
BindingDB Entry DOI: 10.7270/Q2M32WMT |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50187083
(6-(4-methoxyphenethylamino)-N-(2-aminophenyl)nicot...)Show InChI InChI=1S/C21H22N4O2/c1-27-17-9-6-15(7-10-17)12-13-23-20-11-8-16(14-24-20)21(26)25-19-5-3-2-4-18(19)22/h2-11,14H,12-13,22H2,1H3,(H,23,24)(H,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
MethylGene Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant HDAC1 |
Bioorg Med Chem Lett 16: 4048-52 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.005
BindingDB Entry DOI: 10.7270/Q2CF9PP5 |
More data for this
Ligand-Target Pair | |
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