BDBM50187094 CHEMBL375409::N-(2-aminophenyl)-3-(6-(benzylamino)pyridin-3-yl)acrylamide
SMILES: Nc1ccccc1NC(=O)\C=C\c1ccc(NCc2ccccc2)nc1
InChI Key: InChIKey=OAAMYQXWVBCJOH-ACCUITESSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50187094 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50187094
(CHEMBL375409 | N-(2-aminophenyl)-3-(6-(benzylamino...)Show InChI InChI=1S/C21H20N4O/c22-18-8-4-5-9-19(18)25-21(26)13-11-17-10-12-20(24-15-17)23-14-16-6-2-1-3-7-16/h1-13,15H,14,22H2,(H,23,24)(H,25,26)/b13-11+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Menarini Ricerche
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
J Med Chem 51: 1505-29 (2008)
Article DOI: 10.1021/jm7011408
BindingDB Entry DOI: 10.7270/Q2M32WMT |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50187094
(CHEMBL375409 | N-(2-aminophenyl)-3-(6-(benzylamino...)Show InChI InChI=1S/C21H20N4O/c22-18-8-4-5-9-19(18)25-21(26)13-11-17-10-12-20(24-15-17)23-14-16-6-2-1-3-7-16/h1-13,15H,14,22H2,(H,23,24)(H,25,26)/b13-11+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
MethylGene Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant HDAC1 |
Bioorg Med Chem Lett 16: 4048-52 (2006)
Article DOI: 10.1016/j.bmcl.2006.05.005
BindingDB Entry DOI: 10.7270/Q2CF9PP5 |
More data for this
Ligand-Target Pair | |
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