BDBM50187219 (S)-1-(2-benzamido-5-chloro-4-methylphenylsulfonyl)pyrrolidine-2-carboxylic acid::CHEMBL208084

SMILES: Cc1cc(NC(=O)c2ccccc2)c(cc1Cl)S(=O)(=O)N1CCC[C@H]1C(O)=O

InChI Key: InChIKey=HHSSHROLCZKNMM-INIZCTEOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50187219   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50187219 ((S)-1-(2-benzamido-5-chloro-4-methylphenylsulfonyl...) Show SMILES Cc1cc(NC(=O)c2ccccc2)c(cc1Cl)S(=O)(=O)N1CCC[C@H]1C(O)=O Show InChI InChI=1S/C19H19ClN2O5S/c1-12-10-15(21-18(23)13-6-3-2-4-7-13)17(11-14(12)20)28(26,27)22-9-5-8-16(22)19(24)25/h2-4,6-7,10-11,16H,5,8-9H2,1H3,(H,21,23)(H,24,25)/t16-/m0/s1	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of HCV NS5B RNA dependent RNA polymerase				J Med Chem 49: 3052-5 (2006) Article DOI: 10.1021/jm060168g BindingDB Entry DOI: 10.7270/Q2M04517
					More data for this Ligand-Target Pair