BDBM50187220 (S)-1-(2-amino-5-chloro-4-methylphenylsulfonyl)pyrrolidine-2-carboxylic acid::CHEMBL208442

SMILES: Cc1cc(N)c(cc1Cl)S(=O)(=O)N1CCC[C@H]1C(O)=O

InChI Key: InChIKey=RAISWJHVZZKWCB-JTQLQIEISA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50187220   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50187220 ((S)-1-(2-amino-5-chloro-4-methylphenylsulfonyl)pyr...) Show SMILES Cc1cc(N)c(cc1Cl)S(=O)(=O)N1CCC[C@H]1C(O)=O Show InChI InChI=1S/C12H15ClN2O4S/c1-7-5-9(14)11(6-8(7)13)20(18,19)15-4-2-3-10(15)12(16)17/h5-6,10H,2-4,14H2,1H3,(H,16,17)/t10-/m0/s1	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of HCV NS5B RNA dependent RNA polymerase				J Med Chem 49: 3052-5 (2006) Article DOI: 10.1021/jm060168g BindingDB Entry DOI: 10.7270/Q2M04517
					More data for this Ligand-Target Pair