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BDBM50187228 (S)-1-(3,5-dichloro-2-hydroxyphenylsulfonyl)pyrrolidine-2-carboxylic acid::CHEMBL207979

SMILES: OC(=O)[C@@H]1CCCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1O

InChI Key: InChIKey=YYZPIAJBECQUSP-QMMMGPOBSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50187228   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50187228
PNG
((S)-1-(3,5-dichloro-2-hydroxyphenylsulfonyl)pyrrol...)
Show SMILES OC(=O)[C@@H]1CCCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1O
Show InChI InChI=1S/C11H11Cl2NO5S/c12-6-4-7(13)10(15)9(5-6)20(18,19)14-3-1-2-8(14)11(16)17/h4-5,8,15H,1-3H2,(H,16,17)/t8-/m0/s1
UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 770n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of HCV NS5B RNA dependent RNA polymerase


J Med Chem 49: 3052-5 (2006)


Article DOI: 10.1021/jm060168g
BindingDB Entry DOI: 10.7270/Q2M04517
More data for this
Ligand-Target Pair