BDBM50187233 (2S)-1-[(3,5-dichloro-2-hydroxyphenyl)sulfonyl]pyrrolidine-2-carbonitrile::CHEMBL426503

SMILES: Oc1c(Cl)cc(Cl)cc1S(=O)(=O)N1CCC[C@H]1C#N

InChI Key: InChIKey=DNBIVRQVFLPTKE-QMMMGPOBSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50187233   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50187233 ((2S)-1-[(3,5-dichloro-2-hydroxyphenyl)sulfonyl]pyr...) Show SMILES Oc1c(Cl)cc(Cl)cc1S(=O)(=O)N1CCC[C@H]1C#N Show InChI InChI=1S/C11H10Cl2N2O3S/c12-7-4-9(13)11(16)10(5-7)19(17,18)15-3-1-2-8(15)6-14/h4-5,8,16H,1-3H2/t8-/m0/s1	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of HCV NS5B RNA dependent RNA polymerase				J Med Chem 49: 3052-5 (2006) Article DOI: 10.1021/jm060168g BindingDB Entry DOI: 10.7270/Q2M04517
					More data for this Ligand-Target Pair