BDBM50187234 (2R)-1-[(3,5-dichloro-2-hydroxyphenyl)sulfonyl]piperidine-2-carboxylic acid::CHEMBL209167

SMILES: OC(=O)[C@H]1CCCCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1O

InChI Key: InChIKey=MXDUIVIJOFUHPO-SECBINFHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50187234   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50187234 ((2R)-1-[(3,5-dichloro-2-hydroxyphenyl)sulfonyl]pip...) Show SMILES OC(=O)[C@H]1CCCCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1O Show InChI InChI=1S/C12H13Cl2NO5S/c13-7-5-8(14)11(16)10(6-7)21(19,20)15-4-2-1-3-9(15)12(17)18/h5-6,9,16H,1-4H2,(H,17,18)/t9-/m1/s1	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of HCV NS5B RNA dependent RNA polymerase				J Med Chem 49: 3052-5 (2006) Article DOI: 10.1021/jm060168g BindingDB Entry DOI: 10.7270/Q2M04517
					More data for this Ligand-Target Pair