BDBM50187235 (S)-methyl 1-(3,5-dichloro-2-hydroxyphenylsulfonyl)pyrrolidine-2-carboxylate::CHEMBL379608

SMILES: COC(=O)[C@@H]1CCCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1O

InChI Key: InChIKey=YSCYWBYBQXMPCO-VIFPVBQESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50187235   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50187235 ((S)-methyl 1-(3,5-dichloro-2-hydroxyphenylsulfonyl...) Show SMILES COC(=O)[C@@H]1CCCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1O Show InChI InChI=1S/C12H13Cl2NO5S/c1-20-12(17)9-3-2-4-15(9)21(18,19)10-6-7(13)5-8(14)11(10)16/h5-6,9,16H,2-4H2,1H3/t9-/m0/s1	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of HCV NS5B RNA dependent RNA polymerase				J Med Chem 49: 3052-5 (2006) Article DOI: 10.1021/jm060168g BindingDB Entry DOI: 10.7270/Q2M04517
					More data for this Ligand-Target Pair