null
SMILES: CCN(CC)c1ccc(\C=N\NC(=O)CSc2nc3=CC=C=C=c3o2)c(O)c1
InChI Key: InChIKey=JDXRZXIVOQTZJY-CIAFOILYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50187237 (CHEMBL3828515) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 910 | n/a | n/a | n/a | n/a | n/a |
Xiamen University Curated by ChEMBL | Assay Description Binding affinity to RXRalpha-LBD (unknown origin) measured up to 300 sec by surface plasma resonance method | Bioorg Med Chem Lett 26: 3846-9 (2016) BindingDB Entry DOI: 10.7270/Q21N832N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50187237 (CHEMBL3828515) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2.81E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Xiamen University Curated by ChEMBL | Assay Description Antagonist activity at RXRalpha (unknown origin) expressed in HEK293T cells assessed as inhibition of receptor transactivation after 12 hrs in presen... | Bioorg Med Chem Lett 26: 3846-9 (2016) BindingDB Entry DOI: 10.7270/Q21N832N | |||||||||||
More data for this Ligand-Target Pair |