BDBM50187359 (5-Fluoro-1H-indol-2-yl)-(4-methyl-1H-indol-2-yl)-methanone::CHEMBL208640

SMILES: Cc1cccc2[nH]c(cc12)C(=O)c1cc2cc(F)ccc2[nH]1

InChI Key: InChIKey=CJUIAVLIOOCWIE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50187359   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
PDGFR-beta/Platelet-derived growth factor receptor alpha (Mus musculus (mouse))	BDBM50187359 ((5-Fluoro-1H-indol-2-yl)-(4-methyl-1H-indol-2-yl)-...) Show SMILES Cc1cccc2[nH]c(cc12)C(=O)c1cc2cc(F)ccc2[nH]1 Show InChI InChI=1S/C18H13FN2O/c1-10-3-2-4-15-13(10)9-17(21-15)18(22)16-8-11-7-12(19)5-6-14(11)20-16/h2-9,20-21H,1H3	MMDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Inhibition of endogenous PDGFR in Swiss3T3 fibroblasts				J Med Chem 49: 3101-15 (2006) Article DOI: 10.1021/jm058033i BindingDB Entry DOI: 10.7270/Q26T0M7B
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50187359 ((5-Fluoro-1H-indol-2-yl)-(4-methyl-1H-indol-2-yl)-...) Show SMILES Cc1cccc2[nH]c(cc12)C(=O)c1cc2cc(F)ccc2[nH]1 Show InChI InChI=1S/C18H13FN2O/c1-10-3-2-4-15-13(10)9-17(21-15)18(22)16-8-11-7-12(19)5-6-14(11)20-16/h2-9,20-21H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Inhibition of endogenous FLT3 in EOL1 cells				J Med Chem 49: 3101-15 (2006) Article DOI: 10.1021/jm058033i BindingDB Entry DOI: 10.7270/Q26T0M7B
					More data for this Ligand-Target Pair