BDBM50187369 (5-Fluoro-1H-indol-2-yl)-(5-hydroxy-1H-indol-2-yl)-methanone::CHEMBL210989

SMILES: Oc1ccc2[nH]c(cc2c1)C(=O)c1cc2cc(F)ccc2[nH]1

InChI Key: InChIKey=SAQMSZICCVWJSF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50187369   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50187369 ((5-Fluoro-1H-indol-2-yl)-(5-hydroxy-1H-indol-2-yl)...) Show SMILES Oc1ccc2[nH]c(cc2c1)C(=O)c1cc2cc(F)ccc2[nH]1 Show InChI InChI=1S/C17H11FN2O2/c18-11-1-3-13-9(5-11)7-15(19-13)17(22)16-8-10-6-12(21)2-4-14(10)20-16/h1-8,19-21H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Inhibition of endogenous FLT3 in EOL1 cells				J Med Chem 49: 3101-15 (2006) Article DOI: 10.1021/jm058033i BindingDB Entry DOI: 10.7270/Q26T0M7B
					More data for this Ligand-Target Pair
PDGFR-beta/Platelet-derived growth factor receptor alpha (Mus musculus (mouse))	BDBM50187369 ((5-Fluoro-1H-indol-2-yl)-(5-hydroxy-1H-indol-2-yl)...) Show SMILES Oc1ccc2[nH]c(cc2c1)C(=O)c1cc2cc(F)ccc2[nH]1 Show InChI InChI=1S/C17H11FN2O2/c18-11-1-3-13-9(5-11)7-15(19-13)17(22)16-8-10-6-12(21)2-4-14(10)20-16/h1-8,19-21H	MMDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Inhibition of endogenous PDGFR in Swiss3T3 fibroblasts				J Med Chem 49: 3101-15 (2006) Article DOI: 10.1021/jm058033i BindingDB Entry DOI: 10.7270/Q26T0M7B
					More data for this Ligand-Target Pair