null

SMILES: CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)c2ccc(C)cc2)CC1

InChI Key: InChIKey=GDSVOHILVQPEJQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50187387   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50187387 (CHEMBL210537 | N-(3-(4-(4-(4-methylphenylsulfonami...) Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)c2ccc(C)cc2)CC1 Show InChI InChI=1S/C23H32N4O3S/c1-19-8-10-23(11-9-19)31(29,30)24-12-3-4-13-26-14-16-27(17-15-26)22-7-5-6-21(18-22)25-20(2)28/h5-11,18,24H,3-4,12-17H2,1-2H3,(H,25,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor in HEK293 cells				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50187387 (CHEMBL210537 | N-(3-(4-(4-(4-methylphenylsulfonami...) Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)c2ccc(C)cc2)CC1 Show InChI InChI=1S/C23H32N4O3S/c1-19-8-10-23(11-9-19)31(29,30)24-12-3-4-13-26-14-16-27(17-15-26)22-7-5-6-21(18-22)25-20(2)28/h5-11,18,24H,3-4,12-17H2,1-2H3,(H,25,28)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from adrenergic alpha-1 receptor in rat cerebral cortex cells				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50187387 (CHEMBL210537 | N-(3-(4-(4-(4-methylphenylsulfonami...) Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)c2ccc(C)cc2)CC1 Show InChI InChI=1S/C23H32N4O3S/c1-19-8-10-23(11-9-19)31(29,30)24-12-3-4-13-26-14-16-27(17-15-26)22-7-5-6-21(18-22)25-20(2)28/h5-11,18,24H,3-4,12-17H2,1-2H3,(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Inhibition of hERG potassium channel in HEK293 cells by patch clamp assay				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50187387 (CHEMBL210537 | N-(3-(4-(4-(4-methylphenylsulfonami...) Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)c2ccc(C)cc2)CC1 Show InChI InChI=1S/C23H32N4O3S/c1-19-8-10-23(11-9-19)31(29,30)24-12-3-4-13-26-14-16-27(17-15-26)22-7-5-6-21(18-22)25-20(2)28/h5-11,18,24H,3-4,12-17H2,1-2H3,(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human ERG channel				J Med Chem 52: 4266-76 (2009) Article DOI: 10.1021/jm900002x BindingDB Entry DOI: 10.7270/Q2MK6DT2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50187387 (CHEMBL210537 | N-(3-(4-(4-(4-methylphenylsulfonami...) Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)c2ccc(C)cc2)CC1 Show InChI InChI=1S/C23H32N4O3S/c1-19-8-10-23(11-9-19)31(29,30)24-12-3-4-13-26-14-16-27(17-15-26)22-7-5-6-21(18-22)25-20(2)28/h5-11,18,24H,3-4,12-17H2,1-2H3,(H,25,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
Predix Pharmaceuticals Ltd. Curated by ChEMBL					Assay Description Activity against 5HT1A receptor by Gi-[35S]GTPgammaS binding assay				J Med Chem 49: 3116-35 (2006) Article DOI: 10.1021/jm0508641 BindingDB Entry DOI: 10.7270/Q2319VHC
					More data for this Ligand-Target Pair