BDBM50187780 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N4-hydroxy-N1-methyl-N1-phenylpiperidine-1,4-dicarboxamide::CHEMBL425251

SMILES: CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)C(=O)N(C)c1ccccc1)C(=O)NO

InChI Key: InChIKey=WXIYDIUGDDBCAM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50187780   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50187780 (4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N4-hyd...) Show SMILES CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)C(=O)N(C)c1ccccc1)C(=O)NO Show InChI InChI=1S/C25H29N3O6S/c1-3-4-18-34-21-10-12-22(13-11-21)35(32,33)19-25(23(29)26-31)14-16-28(17-15-25)24(30)27(2)20-8-6-5-7-9-20/h5-13,31H,14-19H2,1-2H3,(H,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of TACE by FRET assay				Bioorg Med Chem Lett 16: 3927-31 (2006) Article DOI: 10.1016/j.bmcl.2006.05.026 BindingDB Entry DOI: 10.7270/Q2222TCJ
					More data for this Ligand-Target Pair