BDBM50187911 1,3-dihydro-1-[3-(2-pyrrolidinylethoxy)phenyl]-3-[[3-(trifluoromethyl)phenyl]imino]-2H-indol-2-one::CHEMBL209497

SMILES: FC(F)(F)c1cccc(c1)\N=C1\C(=O)N(c2ccccc12)c1cccc(OCCN2CCCC2)c1

InChI Key: InChIKey=HXCJZIBJTFITNI-QCKNELIISA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50187911   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Galanin receptor 3 (Homo sapiens (Human))	BDBM50187911 (1,3-dihydro-1-[3-(2-pyrrolidinylethoxy)phenyl]-3-[...) Show SMILES FC(F)(F)c1cccc(c1)\N=C1\C(=O)N(c2ccccc12)c1cccc(OCCN2CCCC2)c1 Show InChI InChI=1S/C27H24F3N3O2/c28-27(29,30)19-7-5-8-20(17-19)31-25-23-11-1-2-12-24(23)33(26(25)34)21-9-6-10-22(18-21)35-16-15-32-13-3-4-14-32/h1-2,5-12,17-18H,3-4,13-16H2/b31-25+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]galanin from human galanin Gal3 receptor				Bioorg Med Chem Lett 16: 3950-4 (2006) Article DOI: 10.1016/j.bmcl.2006.05.025 BindingDB Entry DOI: 10.7270/Q2DB81F2
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50187911 (1,3-dihydro-1-[3-(2-pyrrolidinylethoxy)phenyl]-3-[...) Show SMILES FC(F)(F)c1cccc(c1)\N=C1\C(=O)N(c2ccccc12)c1cccc(OCCN2CCCC2)c1 Show InChI InChI=1S/C27H24F3N3O2/c28-27(29,30)19-7-5-8-20(17-19)31-25-23-11-1-2-12-24(23)33(26(25)34)21-9-6-10-22(18-21)35-16-15-32-13-3-4-14-32/h1-2,5-12,17-18H,3-4,13-16H2/b31-25+	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	78	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Binding affinity to human adrenergic alpha1A receptor				Bioorg Med Chem Lett 16: 3950-4 (2006) Article DOI: 10.1016/j.bmcl.2006.05.025 BindingDB Entry DOI: 10.7270/Q2DB81F2
					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM50187911 (1,3-dihydro-1-[3-(2-pyrrolidinylethoxy)phenyl]-3-[...) Show SMILES FC(F)(F)c1cccc(c1)\N=C1\C(=O)N(c2ccccc12)c1cccc(OCCN2CCCC2)c1 Show InChI InChI=1S/C27H24F3N3O2/c28-27(29,30)19-7-5-8-20(17-19)31-25-23-11-1-2-12-24(23)33(26(25)34)21-9-6-10-22(18-21)35-16-15-32-13-3-4-14-32/h1-2,5-12,17-18H,3-4,13-16H2/b31-25+	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	939	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Binding affinity to human dopamine D5 receptor				Bioorg Med Chem Lett 16: 3950-4 (2006) Article DOI: 10.1016/j.bmcl.2006.05.025 BindingDB Entry DOI: 10.7270/Q2DB81F2
					More data for this Ligand-Target Pair