BDBM50187919 1-(3-(3-(diethylamino)-2-hydroxypropoxy)phenyl)-3-(3-(trifluoromethyl)phenylimino)indolin-2-one::CHEMBL378991

SMILES: CCN(CC)CC(O)COc1cccc(c1)N1C(=O)\C(=N\c2cccc(c2)C(F)(F)F)c2ccccc12

InChI Key: InChIKey=FDXFYSXCGJORLT-HMZBKAONSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50187919   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Galanin receptor 3 (Homo sapiens (Human))	BDBM50187919 (1-(3-(3-(diethylamino)-2-hydroxypropoxy)phenyl)-3-...) Show SMILES CCN(CC)CC(O)COc1cccc(c1)N1C(=O)\C(=N\c2cccc(c2)C(F)(F)F)c2ccccc12 Show InChI InChI=1S/C28H28F3N3O3/c1-3-33(4-2)17-22(35)18-37-23-12-8-11-21(16-23)34-25-14-6-5-13-24(25)26(27(34)36)32-20-10-7-9-19(15-20)28(29,30)31/h5-16,22,35H,3-4,17-18H2,1-2H3/b32-26+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]galanin from human galanin Gal3 receptor				Bioorg Med Chem Lett 16: 3950-4 (2006) Article DOI: 10.1016/j.bmcl.2006.05.025 BindingDB Entry DOI: 10.7270/Q2DB81F2
					More data for this Ligand-Target Pair