BindingDB PrimarySearch

BDBM50188025 3-(1-((2-(3,5-dimethoxyphenyl)-5-methyloxazol-4-yl)methyl)-1H-indol-5-yl)-2-ethoxypropanoic acid::CHEMBL211839

SMILES: CCOC(Cc1ccc2n(Cc3nc(oc3C)-c3cc(OC)cc(OC)c3)ccc2c1)C(O)=O

InChI Key: InChIKey=PMZZWDLQGMUYFU-UHFFFAOYSA-N

Data: 2 IC50 3 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50188025
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50188025 (3-(1-((2-(3,5-dimethoxyphenyl)-5-methyloxazol-4-yl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	253	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Binding affinity to PPARalpha by radio ligand binding assay				Bioorg Med Chem Lett 16: 4016-20 (2006) Article DOI: 10.1016/j.bmcl.2006.05.007 BindingDB Entry DOI: 10.7270/Q2MS3SD5
F. Hoffmann-La Roche Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50188025 (3-(1-((2-(3,5-dimethoxyphenyl)-5-methyloxazol-4-yl...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Activity at PPARgamma by luciferase reporter gene transactivation assay relative to edaglitazone				Bioorg Med Chem Lett 16: 4016-20 (2006) Article DOI: 10.1016/j.bmcl.2006.05.007 BindingDB Entry DOI: 10.7270/Q2MS3SD5
F. Hoffmann-La Roche Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50188025 (3-(1-((2-(3,5-dimethoxyphenyl)-5-methyloxazol-4-yl...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Binding affinity to PPARgamma by radio ligand binding assay				Bioorg Med Chem Lett 16: 4016-20 (2006) Article DOI: 10.1016/j.bmcl.2006.05.007 BindingDB Entry DOI: 10.7270/Q2MS3SD5
F. Hoffmann-La Roche Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50188025 (3-(1-((2-(3,5-dimethoxyphenyl)-5-methyloxazol-4-yl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	90	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Activity at PPARalpha by luciferase reporter gene transactivation assay relative to farglitazar				Bioorg Med Chem Lett 16: 4016-20 (2006) Article DOI: 10.1016/j.bmcl.2006.05.007 BindingDB Entry DOI: 10.7270/Q2MS3SD5
F. Hoffmann-La Roche Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50188025 (3-(1-((2-(3,5-dimethoxyphenyl)-5-methyloxazol-4-yl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Activity at PPARdelta by luciferase reporter gene transactivation assay relative to GW 501516				Bioorg Med Chem Lett 16: 4016-20 (2006) Article DOI: 10.1016/j.bmcl.2006.05.007 BindingDB Entry DOI: 10.7270/Q2MS3SD5
F. Hoffmann-La Roche Ltd Curated by ChEMBL					More data for this Ligand-Target Pair