BDBM50188092 1-(4-iodobenzyl)-1H-imidazole::4-iodobenzyl imidazole::CHEMBL427399
SMILES: Ic1ccc(Cn2ccnc2)cc1
InChI Key: InChIKey=WZKZRSOWLZKJCL-UHFFFAOYSA-N
Data: 6 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome P450 17A1 (Rattus norvegicus (Rat)) | BDBM50188092 (1-(4-iodobenzyl)-1H-imidazole | 4-iodobenzyl imida...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 1.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University Curated by ChEMBL | Assay Description Inhibition of rat microsomal 17,20-lyase component of P450-17alpha | Bioorg Med Chem Lett 16: 4011-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.070 BindingDB Entry DOI: 10.7270/Q27M07J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 17A1 (Rattus norvegicus (Rat)) | BDBM50188092 (1-(4-iodobenzyl)-1H-imidazole | 4-iodobenzyl imida...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 1.01E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University Curated by ChEMBL | Assay Description Inhibition of rat microsomal 17alpha-hydroxylase component of P450-17alpha | Bioorg Med Chem Lett 16: 4011-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.070 BindingDB Entry DOI: 10.7270/Q27M07J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 17A1 (Rattus norvegicus (Rat)) | BDBM50188092 (1-(4-iodobenzyl)-1H-imidazole | 4-iodobenzyl imida...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 164 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the West of Scotland Curated by ChEMBL | Assay Description Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alpha | Bioorg Med Chem Lett 20: 5345-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.100 BindingDB Entry DOI: 10.7270/Q2DF6RF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 17A1 (Rattus norvegicus (Rat)) | BDBM50188092 (1-(4-iodobenzyl)-1H-imidazole | 4-iodobenzyl imida...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 1.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the West of Scotland Curated by ChEMBL | Assay Description Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alpha | Bioorg Med Chem Lett 19: 4698-701 (2009) Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 17A1 (Rattus norvegicus (Rat)) | BDBM50188092 (1-(4-iodobenzyl)-1H-imidazole | 4-iodobenzyl imida...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 730 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the West of Scotland Curated by ChEMBL | Assay Description Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alpha | Bioorg Med Chem Lett 20: 5345-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.100 BindingDB Entry DOI: 10.7270/Q2DF6RF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 17A1 (Rattus norvegicus (Rat)) | BDBM50188092 (1-(4-iodobenzyl)-1H-imidazole | 4-iodobenzyl imida...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 1.01E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the West of Scotland Curated by ChEMBL | Assay Description Inhibition of 17alpha-hydroxylase activity of rat testicular microsomal P450-17alpha | Bioorg Med Chem Lett 19: 4698-701 (2009) Article DOI: 10.1016/j.bmcl.2009.06.070 BindingDB Entry DOI: 10.7270/Q29K4B72 | |||||||||||
More data for this Ligand-Target Pair |