BDBM50188236 CHEMBL3827742
SMILES: COCCN(CC(=O)N(CCCCN)CC(=O)N(CCCCN)CC(N)=O)C(=O)CN(Cc1ccc2OCOc2c1)C(=O)CN(NC(=O)Nc1ccccc1)C(=O)CN(NC(=O)c1ccc(Cl)cc1)C(=O)CN(NC(=O)CCOC)C(=O)CN(C)C(=O)Cn1nc(oc1=O)-c1ccc(s1)-c1ccc(Br)cc1
InChI Key: InChIKey=OZKACVYHVAJULB-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Platelet-activating factor acetylhydrolase IB subunit beta (Homo sapiens (Human)) | BDBM50188236 (CHEMBL3827742) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.61E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shiv Nadar University Curated by ChEMBL | Assay Description Inhibition of PAFAH1B2 (unknown origin) using 2-thiol-PAF as substrate by Ellman's assay | Bioorg Med Chem 24: 3953-3963 (2016) BindingDB Entry DOI: 10.7270/Q2668G45 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-activating factor acetylhydrolase IB subunit beta (Homo sapiens (Human)) | BDBM50188236 (CHEMBL3827742) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shiv Nadar University Curated by ChEMBL | Assay Description Time-dependent inhibition of PAFAH1B2 (unknown origin) using 2-thiol-PAF as substrate by Ellman's assay | Bioorg Med Chem 24: 3953-3963 (2016) BindingDB Entry DOI: 10.7270/Q2668G45 | |||||||||||
More data for this Ligand-Target Pair |