BDBM50188325 3-(4-fluoro-3-(trifluoromethyl)phenyl)-1-(3-(4-methylpiperazin-1-yl)propyl)-1-((1S,2R,5S)-5-(thiazol-2-yl)bicyclo[3.1.0]hexan-2-yl)urea::CHEMBL386512

SMILES: CN1CCN(CCCN([C@@H]2CC[C@@]3(C[C@H]23)c2nccs2)C(=O)Nc2ccc(F)c(c2)C(F)(F)F)CC1

InChI Key: InChIKey=FOKNOQMQHNCTGM-ZYKOEDHHSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50188325   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50188325 (3-(4-fluoro-3-(trifluoromethyl)phenyl)-1-(3-(4-met...) Show SMILES CN1CCN(CCCN([C@@H]2CC[C@@]3(C[C@H]23)c2nccs2)C(=O)Nc2ccc(F)c(c2)C(F)(F)F)CC1 Show InChI InChI=1S/C25H31F4N5OS/c1-32-10-12-33(13-11-32)8-2-9-34(21-5-6-24(16-19(21)24)22-30-7-14-36-22)23(35)31-17-3-4-20(26)18(15-17)25(27,28)29/h3-4,7,14-15,19,21H,2,5-6,8-13,16H2,1H3,(H,31,35)/t19-,21-,24+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity to MCHR1				Bioorg Med Chem Lett 16: 4262-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.069 BindingDB Entry DOI: 10.7270/Q2BC3Z5G
					More data for this Ligand-Target Pair