BDBM50188331 3-(3-chloro-4-fluorophenyl)-1-(3-(4-methylpiperazin-1-yl)propyl)-1-((1S,2R,5S)-5-(3-(pyrrolidin-1-yl)phenyl)bicyclo[3.1.0]hexan-2-yl)urea::CHEMBL213840

SMILES: CN1CCN(CCCN([C@@H]2CC[C@@]3(C[C@H]23)c2cccc(c2)N2CCCC2)C(=O)Nc2ccc(F)c(Cl)c2)CC1

InChI Key: InChIKey=MWHZSDYFOZVOAE-XOPMNVLASA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50188331   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50188331 (3-(3-chloro-4-fluorophenyl)-1-(3-(4-methylpiperazi...) Show SMILES CN1CCN(CCCN([C@@H]2CC[C@@]3(C[C@H]23)c2cccc(c2)N2CCCC2)C(=O)Nc2ccc(F)c(Cl)c2)CC1 Show InChI InChI=1S/C31H41ClFN5O/c1-35-16-18-36(19-17-35)12-5-15-38(30(39)34-24-8-9-28(33)27(32)21-24)29-10-11-31(22-26(29)31)23-6-4-7-25(20-23)37-13-2-3-14-37/h4,6-9,20-21,26,29H,2-3,5,10-19,22H2,1H3,(H,34,39)/t26-,29-,31-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity to MCHR1				Bioorg Med Chem Lett 16: 4262-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.069 BindingDB Entry DOI: 10.7270/Q2BC3Z5G
					More data for this Ligand-Target Pair