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SMILES: CNC(=O)c1ccc(cc1)[C@@]12C[C@@H]1[C@@H](CC2)N(CCCN1CCN(C)CC1)C(=O)Nc1ccc(F)c(c1)C(F)(F)F

InChI Key: InChIKey=UQXNHWZJPIQLTE-PIRIWWGTSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50188332   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50188332
PNG
(3-(4-fluoro-3-(trifluoromethyl)phenyl)-1-((1S,2R,5...)
Show SMILES CNC(=O)c1ccc(cc1)[C@@]12C[C@@H]1[C@@H](CC2)N(CCCN1CCN(C)CC1)C(=O)Nc1ccc(F)c(c1)C(F)(F)F
Show InChI InChI=1S/C30H37F4N5O2/c1-35-27(40)20-4-6-21(7-5-20)29-11-10-26(24(29)19-29)39(13-3-12-38-16-14-37(2)15-17-38)28(41)36-22-8-9-25(31)23(18-22)30(32,33)34/h4-9,18,24,26H,3,10-17,19H2,1-2H3,(H,35,40)(H,36,41)/t24-,26-,29-/m1/s1
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 17n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Binding affinity to MCHR1

Bioorg Med Chem Lett 16: 4262-5 (2006)


Article DOI: 10.1016/j.bmcl.2006.05.069
BindingDB Entry DOI: 10.7270/Q2BC3Z5G
More data for this
Ligand-Target Pair