BDBM50188480 CHEMBL59426::Pro-Gly::[((S)-Pyrrolidine-2-carbonyl)-amino]-acetic acid::[(Pyrrolidine-2-carbonyl)-amino]-acetic acid

SMILES: OC(=O)CNC(=O)[C@@H]1CCCN1

InChI Key: InChIKey=RNKSNIBMTUYWSH-YFKPBYRVSA-N

Data: 2 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50188480   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oligopeptide transporter, kidney isoform (Rattus norvegicus)	BDBM50188480 (CHEMBL59426 | Pro-Gly | [((S)-Pyrrolidine-2-carbon...) Show SMILES OC(=O)CNC(=O)[C@@H]1CCCN1 Show InChI InChI=1S/C7H12N2O3/c10-6(11)4-9-7(12)5-2-1-3-8-5/h5,8H,1-4H2,(H,9,12)(H,10,11)/t5-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Hospital Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of Gly-Sar uptake in PEPT2-expressing LLC-PK1 cells				Pflugers Arch 440: 679-84 (2000) Article DOI: 10.1007/s004240000339 BindingDB Entry DOI: 10.7270/Q2CR5X6C
					More data for this Ligand-Target Pair
Solute carrier family 15 member 1 (Rattus norvegicus)	BDBM50188480 (CHEMBL59426 | Pro-Gly | [((S)-Pyrrolidine-2-carbon...) Show SMILES OC(=O)CNC(=O)[C@@H]1CCCN1 Show InChI InChI=1S/C7H12N2O3/c10-6(11)4-9-7(12)5-2-1-3-8-5/h5,8H,1-4H2,(H,9,12)(H,10,11)/t5-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.30E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Hospital Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of Gly-Sar uptake in PEPT1-expressing LLC-PK1 cells				Pflugers Arch 440: 679-84 (2000) Article DOI: 10.1007/s004240000339 BindingDB Entry DOI: 10.7270/Q2CR5X6C
					More data for this Ligand-Target Pair
Oligopeptide transporter small intestine isoform (Homo sapiens (Human))	BDBM50188480 (CHEMBL59426 | Pro-Gly | [((S)-Pyrrolidine-2-carbon...) Show SMILES OC(=O)CNC(=O)[C@@H]1CCCN1 Show InChI InChI=1S/C7H12N2O3/c10-6(11)4-9-7(12)5-2-1-3-8-5/h5,8H,1-4H2,(H,9,12)(H,10,11)/t5-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.60E+7	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity to human PEPT1 assessed as inhibition of [14C]Gly-Sar uptake in MDCK cells				J Med Chem 49: 3636-44 (2006) Article DOI: 10.1021/jm0511029 BindingDB Entry DOI: 10.7270/Q2P55P9R
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Homo sapiens (Human))	BDBM50188480 (CHEMBL59426 | Pro-Gly | [((S)-Pyrrolidine-2-carbon...) Show SMILES OC(=O)CNC(=O)[C@@H]1CCCN1 Show InChI InChI=1S/C7H12N2O3/c10-6(11)4-9-7(12)5-2-1-3-8-5/h5,8H,1-4H2,(H,9,12)(H,10,11)/t5-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.70E+7	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Biological activity was measured against Angiotensin I converting enzyme				J Med Chem 38: 2705-13 (1995) BindingDB Entry DOI: 10.7270/Q2GX4CSN
					More data for this Ligand-Target Pair