Found 7 hits for monomerid = 50188491 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Oligopeptide transporter, kidney isoform
(Rattus norvegicus) | BDBM50188491
((S)-2-(2-Amino-acetylamino)-3-phenyl-propionic aci...)Show InChI InChI=1S/C11H14N2O3/c12-7-10(14)13-9(11(15)16)6-8-4-2-1-3-5-8/h1-5,9H,6-7,12H2,(H,13,14)(H,15,16)/t9-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University Hospital
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of Gly-Sar uptake in PEPT2-expressing LLC-PK1 cells |
Pflugers Arch 440: 679-84 (2000)
Article DOI: 10.1007/s004240000339 BindingDB Entry DOI: 10.7270/Q2CR5X6C |
More data for this Ligand-Target Pair | |
Solute carrier family 15 member 1
(Rattus norvegicus) | BDBM50188491
((S)-2-(2-Amino-acetylamino)-3-phenyl-propionic aci...)Show InChI InChI=1S/C11H14N2O3/c12-7-10(14)13-9(11(15)16)6-8-4-2-1-3-5-8/h1-5,9H,6-7,12H2,(H,13,14)(H,15,16)/t9-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University Hospital
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of Gly-Sar uptake in PEPT1-expressing LLC-PK1 cells |
Pflugers Arch 440: 679-84 (2000)
Article DOI: 10.1007/s004240000339 BindingDB Entry DOI: 10.7270/Q2CR5X6C |
More data for this Ligand-Target Pair | |
Oligopeptide transporter small intestine isoform
(Homo sapiens (Human)) | BDBM50188491
((S)-2-(2-Amino-acetylamino)-3-phenyl-propionic aci...)Show InChI InChI=1S/C11H14N2O3/c12-7-10(14)13-9(11(15)16)6-8-4-2-1-3-5-8/h1-5,9H,6-7,12H2,(H,13,14)(H,15,16)/t9-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Binding affinity to human PEPT1 assessed as inhibition of [14C]Gly-Sar uptake in MDCK cells |
J Med Chem 49: 3636-44 (2006)
Article DOI: 10.1021/jm0511029 BindingDB Entry DOI: 10.7270/Q2P55P9R |
More data for this Ligand-Target Pair | |
Angiotensin-converting enzyme
(Homo sapiens (Human)) | BDBM50188491
((S)-2-(2-Amino-acetylamino)-3-phenyl-propionic aci...)Show InChI InChI=1S/C11H14N2O3/c12-7-10(14)13-9(11(15)16)6-8-4-2-1-3-5-8/h1-5,9H,6-7,12H2,(H,13,14)(H,15,16)/t9-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 6.31E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago
Curated by ChEMBL
| Assay Description Biological activity was measured against Angiotensin I converting enzyme |
J Med Chem 38: 2705-13 (1995)
BindingDB Entry DOI: 10.7270/Q2GX4CSN |
More data for this Ligand-Target Pair | |
Oligopeptide transporter small intestine isoform
(Homo sapiens (Human)) | BDBM50188491
((S)-2-(2-Amino-acetylamino)-3-phenyl-propionic aci...)Show InChI InChI=1S/C11H14N2O3/c12-7-10(14)13-9(11(15)16)6-8-4-2-1-3-5-8/h1-5,9H,6-7,12H2,(H,13,14)(H,15,16)/t9-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.30E+5 | n/a | n/a | n/a | n/a |
Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Activation of human PEPT1 expressed in MDCK cells |
J Med Chem 49: 3636-44 (2006)
Article DOI: 10.1021/jm0511029 BindingDB Entry DOI: 10.7270/Q2P55P9R |
More data for this Ligand-Target Pair | |
Angiotensin-converting enzyme
(Homo sapiens (Human)) | BDBM50188491
((S)-2-(2-Amino-acetylamino)-3-phenyl-propionic aci...)Show InChI InChI=1S/C11H14N2O3/c12-7-10(14)13-9(11(15)16)6-8-4-2-1-3-5-8/h1-5,9H,6-7,12H2,(H,13,14)(H,15,16)/t9-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.75E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Tianjin University
Curated by ChEMBL
| Assay Description Inhibition of ACE (unknown origin) |
Eur J Med Chem 84: 100-6 (2014)
Article DOI: 10.1016/j.ejmech.2014.07.015 BindingDB Entry DOI: 10.7270/Q29025F2 |
More data for this Ligand-Target Pair | |
Angiotensin-converting enzyme
(Homo sapiens (Human)) | BDBM50188491
((S)-2-(2-Amino-acetylamino)-3-phenyl-propionic aci...)Show InChI InChI=1S/C11H14N2O3/c12-7-10(14)13-9(11(15)16)6-8-4-2-1-3-5-8/h1-5,9H,6-7,12H2,(H,13,14)(H,15,16)/t9-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 6.03E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Washington University
Curated by ChEMBL
| Assay Description Inhibitory activity against angiotensin converting enzyme (ACE) |
J Med Chem 36: 2390-403 (1993)
BindingDB Entry DOI: 10.7270/Q2Z320V9 |
More data for this Ligand-Target Pair | |