BDBM50188916 (2S)-methyl 3-(2,4-dichlorophenyl)-2-(2-(2-(methylamino)pyrimidin-4-yl)thiophene-5-carboxamido)propanoate::CHEMBL210115

SMILES: CNc1nccc(n1)-c1ccc(s1)C(=O)N[C@@H](Cc1ccc(Cl)cc1Cl)C(=O)OC

InChI Key: InChIKey=AONUCCZONNRUNR-HNNXBMFYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50188916   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase AKT (Homo sapiens (Human))	BDBM50188916 ((2S)-methyl 3-(2,4-dichlorophenyl)-2-(2-(2-(methyl...) Show SMILES CNc1nccc(n1)-c1ccc(s1)C(=O)N[C@@H](Cc1ccc(Cl)cc1Cl)C(=O)OC Show InChI InChI=1S/C20H18Cl2N4O3S/c1-23-20-24-8-7-14(26-20)16-5-6-17(30-16)18(27)25-15(19(28)29-2)9-11-3-4-12(21)10-13(11)22/h3-8,10,15H,9H2,1-2H3,(H,25,27)(H,23,24,26)/t15-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chiron Corporation Curated by ChEMBL					Assay Description Inhibition of AKT3 in presence of 0.2 uM ATP				Bioorg Med Chem Lett 16: 4163-8 (2006) Article DOI: 10.1016/j.bmcl.2006.05.092 BindingDB Entry DOI: 10.7270/Q24M945C
					More data for this Ligand-Target Pair