BDBM50188919 3-(4-fluorophenyl)-N-(5-(2-(methylamino)pyrimidin-4-yl)thiophen-2-yl)propanamide::CHEMBL213181

SMILES: CNc1nccc(n1)-c1ccc(NC(=O)CCc2ccc(F)cc2)s1

InChI Key: InChIKey=ORMFNQBOCNXRRU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50188919   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase AKT (Homo sapiens (Human))	BDBM50188919 (3-(4-fluorophenyl)-N-(5-(2-(methylamino)pyrimidin-...) Show SMILES CNc1nccc(n1)-c1ccc(NC(=O)CCc2ccc(F)cc2)s1 Show InChI InChI=1S/C18H17FN4OS/c1-20-18-21-11-10-14(22-18)15-7-9-17(25-15)23-16(24)8-4-12-2-5-13(19)6-3-12/h2-3,5-7,9-11H,4,8H2,1H3,(H,23,24)(H,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chiron Corporation Curated by ChEMBL					Assay Description Inhibition of AKT3 in presence of 0.2 uM ATP				Bioorg Med Chem Lett 16: 4163-8 (2006) Article DOI: 10.1016/j.bmcl.2006.05.092 BindingDB Entry DOI: 10.7270/Q24M945C
					More data for this Ligand-Target Pair