BDBM50188926 CHEMBL209475::N-(2-aminoethyl)-5-(2-(methylamino)pyrimidin-4-yl)thiophene-2-carboxamide

SMILES: CNc1nccc(n1)-c1ccc(s1)C(=O)NCCN

InChI Key: InChIKey=BMCNSGBPGWNGAW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50188926   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase AKT (Homo sapiens (Human))	BDBM50188926 (CHEMBL209475 | N-(2-aminoethyl)-5-(2-(methylamino)...) Show SMILES CNc1nccc(n1)-c1ccc(s1)C(=O)NCCN Show InChI InChI=1S/C12H15N5OS/c1-14-12-16-6-4-8(17-12)9-2-3-10(19-9)11(18)15-7-5-13/h2-4,6H,5,7,13H2,1H3,(H,15,18)(H,14,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chiron Corporation Curated by ChEMBL					Assay Description Inhibition of AKT3 in presence of 0.2 uM ATP				Bioorg Med Chem Lett 16: 4163-8 (2006) Article DOI: 10.1016/j.bmcl.2006.05.092 BindingDB Entry DOI: 10.7270/Q24M945C
					More data for this Ligand-Target Pair