BDBM50188931 4-fluorobenzyl 5-(2-(methylamino)pyrimidin-4-yl)thiophen-2-ylcarbamate::CHEMBL214339

SMILES: CNc1nccc(n1)-c1ccc(NC(=O)OCc2ccc(F)cc2)s1

InChI Key: InChIKey=YYVSCAHJOXSJPU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50188931   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase AKT (Homo sapiens (Human))	BDBM50188931 (4-fluorobenzyl 5-(2-(methylamino)pyrimidin-4-yl)th...) Show SMILES CNc1nccc(n1)-c1ccc(NC(=O)OCc2ccc(F)cc2)s1 Show InChI InChI=1S/C17H15FN4O2S/c1-19-16-20-9-8-13(21-16)14-6-7-15(25-14)22-17(23)24-10-11-2-4-12(18)5-3-11/h2-9H,10H2,1H3,(H,22,23)(H,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	7.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chiron Corporation Curated by ChEMBL					Assay Description Inhibition of AKT3 in presence of 0.2 uM ATP				Bioorg Med Chem Lett 16: 4163-8 (2006) Article DOI: 10.1016/j.bmcl.2006.05.092 BindingDB Entry DOI: 10.7270/Q24M945C
					More data for this Ligand-Target Pair