BDBM50188947 CHEMBL377568::N-(2,4-dichlorophenethyl)-5-(2-aminopyrimidin-4-yl)thiophene-2-carboxamide

SMILES: Nc1nccc(n1)-c1ccc(s1)C(=O)NCCc1ccc(Cl)cc1Cl

InChI Key: InChIKey=UZJHGGDNLWLNIC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50188947   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase AKT (Homo sapiens (Human))	BDBM50188947 (CHEMBL377568 | N-(2,4-dichlorophenethyl)-5-(2-amin...) Show SMILES Nc1nccc(n1)-c1ccc(s1)C(=O)NCCc1ccc(Cl)cc1Cl Show InChI InChI=1S/C17H14Cl2N4OS/c18-11-2-1-10(12(19)9-11)5-7-21-16(24)15-4-3-14(25-15)13-6-8-22-17(20)23-13/h1-4,6,8-9H,5,7H2,(H,21,24)(H2,20,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
Chiron Corporation Curated by ChEMBL					Assay Description Inhibition of AKT3 in presence of 0.2 uM ATP				Bioorg Med Chem Lett 16: 4163-8 (2006) Article DOI: 10.1016/j.bmcl.2006.05.092 BindingDB Entry DOI: 10.7270/Q24M945C
					More data for this Ligand-Target Pair