BDBM50189604 4-fluoro-3-((2-(pyridin-2-ylamino)thiazol-5-ylmethyl)amino)-N-(pyridin-2-ylmethyl)benzamide::CHEMBL208788

SMILES: Fc1ccc(cc1NCc1cnc(Nc2ccccn2)s1)C(=O)NCc1ccccn1

InChI Key: InChIKey=DYLWWKFXSFUWIY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50189604   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50189604 (4-fluoro-3-((2-(pyridin-2-ylamino)thiazol-5-ylmeth...) Show SMILES Fc1ccc(cc1NCc1cnc(Nc2ccccn2)s1)C(=O)NCc1ccccn1 Show InChI InChI=1S/C22H19FN6OS/c23-18-8-7-15(21(30)27-12-16-5-1-3-9-24-16)11-19(18)26-13-17-14-28-22(31-17)29-20-6-2-4-10-25-20/h1-11,14,26H,12-13H2,(H,27,30)(H,25,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of FLK1				J Med Chem 49: 3766-9 (2006) Article DOI: 10.1021/jm060347y BindingDB Entry DOI: 10.7270/Q2PG1RBM
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