BDBM50189606 4-fluoro-N-methyl-3-((2-(pyridin-2-ylamino)thiazol-5-ylmethyl)amino)benzamide::CHEMBL212304

SMILES: CNC(=O)c1ccc(F)c(NCc2cnc(Nc3ccccn3)s2)c1

InChI Key: InChIKey=UCMYSEIPKICNET-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50189606   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50189606 (4-fluoro-N-methyl-3-((2-(pyridin-2-ylamino)thiazol...) Show SMILES CNC(=O)c1ccc(F)c(NCc2cnc(Nc3ccccn3)s2)c1 Show InChI InChI=1S/C17H16FN5OS/c1-19-16(24)11-5-6-13(18)14(8-11)21-9-12-10-22-17(25-12)23-15-4-2-3-7-20-15/h2-8,10,21H,9H2,1H3,(H,19,24)(H,20,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of FLK1				J Med Chem 49: 3766-9 (2006) Article DOI: 10.1021/jm060347y BindingDB Entry DOI: 10.7270/Q2PG1RBM
					More data for this Ligand-Target Pair