BDBM50189608 CHEMBL379661::N-methoxy-3-((2-(pyridin-2-ylamino)thiazol-5-ylthio)methyl)benzamide

SMILES: CONC(=O)c1cccc(CSc2cnc(Nc3ccccn3)s2)c1

InChI Key: InChIKey=KXQQIVCSTCQZAB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50189608   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50189608 (CHEMBL379661 | N-methoxy-3-((2-(pyridin-2-ylamino)...) Show SMILES CONC(=O)c1cccc(CSc2cnc(Nc3ccccn3)s2)c1 Show InChI InChI=1S/C17H16N4O2S2/c1-23-21-16(22)13-6-4-5-12(9-13)11-24-15-10-19-17(25-15)20-14-7-2-3-8-18-14/h2-10H,11H2,1H3,(H,21,22)(H,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of FLK1				J Med Chem 49: 3766-9 (2006) Article DOI: 10.1021/jm060347y BindingDB Entry DOI: 10.7270/Q2PG1RBM
					More data for this Ligand-Target Pair