BDBM50189610 4-fluoro-N-(2-morpholinoethyl)-3-((2-(pyridin-2-ylamino)thiazol-5-ylmethyl)amino)benzamide::CHEMBL211060

SMILES: Fc1ccc(cc1NCc1cnc(Nc2ccccn2)s1)C(=O)NCCN1CCOCC1

InChI Key: InChIKey=SDGYSKVZUGRTGM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50189610   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50189610 (4-fluoro-N-(2-morpholinoethyl)-3-((2-(pyridin-2-yl...) Show SMILES Fc1ccc(cc1NCc1cnc(Nc2ccccn2)s1)C(=O)NCCN1CCOCC1 Show InChI InChI=1S/C22H25FN6O2S/c23-18-5-4-16(21(30)25-7-8-29-9-11-31-12-10-29)13-19(18)26-14-17-15-27-22(32-17)28-20-3-1-2-6-24-20/h1-6,13,15,26H,7-12,14H2,(H,25,30)(H,24,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of FLK1				J Med Chem 49: 3766-9 (2006) Article DOI: 10.1021/jm060347y BindingDB Entry DOI: 10.7270/Q2PG1RBM
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