BDBM50189613 CHEMBL379370::N-cyclopropyl-4-fluoro-3-((2-(pyridin-2-ylamino)thiazol-5-ylmethyl)amino)benzamide

SMILES: Fc1ccc(cc1NCc1cnc(Nc2ccccn2)s1)C(=O)NC1CC1

InChI Key: InChIKey=CPJIMFZYHUTSJD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50189613   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50189613 (CHEMBL379370 | N-cyclopropyl-4-fluoro-3-((2-(pyrid...) Show SMILES Fc1ccc(cc1NCc1cnc(Nc2ccccn2)s1)C(=O)NC1CC1 Show InChI InChI=1S/C19H18FN5OS/c20-15-7-4-12(18(26)24-13-5-6-13)9-16(15)22-10-14-11-23-19(27-14)25-17-3-1-2-8-21-17/h1-4,7-9,11,13,22H,5-6,10H2,(H,24,26)(H,21,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of FLK1				J Med Chem 49: 3766-9 (2006) Article DOI: 10.1021/jm060347y BindingDB Entry DOI: 10.7270/Q2PG1RBM
					More data for this Ligand-Target Pair