BDBM50189614 CHEMBL207520::N-methyl-3-((2-(pyridin-2-ylamino)thiazol-5-ylmethyl)amino)benzamide

SMILES: CNC(=O)c1cccc(NCc2cnc(Nc3ccccn3)s2)c1

InChI Key: InChIKey=LERGUDCLTSKXHR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50189614   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50189614 (CHEMBL207520 | N-methyl-3-((2-(pyridin-2-ylamino)t...) Show SMILES CNC(=O)c1cccc(NCc2cnc(Nc3ccccn3)s2)c1 Show InChI InChI=1S/C17H17N5OS/c1-18-16(23)12-5-4-6-13(9-12)20-10-14-11-21-17(24-14)22-15-7-2-3-8-19-15/h2-9,11,20H,10H2,1H3,(H,18,23)(H,19,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of FLK1				J Med Chem 49: 3766-9 (2006) Article DOI: 10.1021/jm060347y BindingDB Entry DOI: 10.7270/Q2PG1RBM
					More data for this Ligand-Target Pair