BDBM50189759 5-((5-(2-bromo-4-nitrophenyl)furan-2-yl)methylene)-2-thioxothiazolidin-4-one::CHEMBL209560

SMILES: [O-][N+](=O)c1ccc(-c2ccc(\C=C3/SC(=S)NC3=O)o2)c(Br)c1

InChI Key: InChIKey=HNUSJOUJWWUCHW-SDQBBNPISA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50189759   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50189759 (5-((5-(2-bromo-4-nitrophenyl)furan-2-yl)methylene)...) Show SMILES [O-][N+](=O)c1ccc(-c2ccc(\C=C3/SC(=S)NC3=O)o2)c(Br)c1 Show InChI InChI=1S/C14H7BrN2O4S2/c15-10-5-7(17(19)20)1-3-9(10)11-4-2-8(21-11)6-12-13(18)16-14(22)23-12/h1-6H,(H,16,18,22)/b12-6-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Serono Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma				J Med Chem 49: 3857-71 (2006) Article DOI: 10.1021/jm0601598 BindingDB Entry DOI: 10.7270/Q2DZ07X0
					More data for this Ligand-Target Pair