BDBM50189783 CHEMBL3828122

SMILES: CC(Oc1ccc2[nH]nc(-c3nc4cc(ccc4[nH]3)N3C[C@H](C)N[C@H](C)C3)c2c1)c1c(Cl)cncc1Cl

InChI Key: InChIKey=JZMMRIIMJLFYOI-XYPWUTKMSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50189783   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50189783 (CHEMBL3828122) Show SMILES CC(Oc1ccc2[nH]nc(-c3nc4cc(ccc4[nH]3)N3C[C@H](C)N[C@H](C)C3)c2c1)c1c(Cl)cncc1Cl |r| Show InChI InChI=1S/C27H27Cl2N7O/c1-14-12-36(13-15(2)31-14)17-4-6-23-24(8-17)33-27(32-23)26-19-9-18(5-7-22(19)34-35-26)37-16(3)25-20(28)10-30-11-21(25)29/h4-11,14-16,31H,12-13H2,1-3H3,(H,32,33)(H,34,35)/t14-,15+,16?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science& Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human FGFR1 using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISA				J Med Chem 59: 6690-708 (2016) BindingDB Entry DOI: 10.7270/Q2474CT3
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50189783 (CHEMBL3828122) Show SMILES CC(Oc1ccc2[nH]nc(-c3nc4cc(ccc4[nH]3)N3C[C@H](C)N[C@H](C)C3)c2c1)c1c(Cl)cncc1Cl |r| Show InChI InChI=1S/C27H27Cl2N7O/c1-14-12-36(13-15(2)31-14)17-4-6-23-24(8-17)33-27(32-23)26-19-9-18(5-7-22(19)34-35-26)37-16(3)25-20(28)10-30-11-21(25)29/h4-11,14-16,31H,12-13H2,1-3H3,(H,32,33)(H,34,35)/t14-,15+,16?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science& Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human VEGFR2 using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISA				J Med Chem 59: 6690-708 (2016) BindingDB Entry DOI: 10.7270/Q2474CT3
					More data for this Ligand-Target Pair