BDBM50189792 CHEMBL3828317

SMILES: C(Oc1ccc2[nH]nc(-c3nc4cc(ccc4[nH]3)N3CCCCC3)c2c1)c1ccccn1

InChI Key: InChIKey=DSAYKPYMTVBWGX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50189792   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50189792 (CHEMBL3828317) Show SMILES C(Oc1ccc2[nH]nc(-c3nc4cc(ccc4[nH]3)N3CCCCC3)c2c1)c1ccccn1 Show InChI InChI=1S/C25H24N6O/c1-4-12-31(13-5-1)18-7-9-22-23(14-18)28-25(27-22)24-20-15-19(8-10-21(20)29-30-24)32-16-17-6-2-3-11-26-17/h2-3,6-11,14-15H,1,4-5,12-13,16H2,(H,27,28)(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science& Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human FGFR1 using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISA				J Med Chem 59: 6690-708 (2016) BindingDB Entry DOI: 10.7270/Q2474CT3
					More data for this Ligand-Target Pair